I had a weekend home in central Michigan. It was a “modern build”, 1996. Built as a normal home, with normal plumbing, electrical, HVAC. I mention modern and normal since many homes in that area were built as cottages for seasonal use only. I had 6” insulated walls, double pane windows, and insulated crawl space walls (4' tall batt insulation on the block walls), etc. We never “closed” the home for the winter.
Gas water heater in garage. We wrapped that exposed plumbing with thermostatically controlled automatic UL listed heat tape. When leaving, we kept the heat at 52 degrees inside, turned off the breaker to the well pump, turned down the water heater to "VACATION" (lowest) setting. Crawl space vents closed, though it never got cold in the crawl space. While we never added antifreeze to the toilets we often added either white vinegar or bleach to prevent organic growth in the toilet bowls.
The only times we had frozen pipes was when power to the heat tape failed; it had been plugged into a garage GFCI that tripped. We changed that by plugging into an indoor outlet. This only happened when there was extended single digit temps… those were generally in those dangerous eight weeks of January and February, the worst part of winter in Michigan, and in most places.
In later years we were able to get high speed internet there, and an internet thermostat which allowed us to check things remotely. We augmented that with Wyze cameras too.
A lot of the protocols you will need depend on how well that house is built. Also, check with how your neighbors up state there deal with it as well…